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Key gaps to address: dose-response in humans, safety/tolerability profiles across populations, interaction effects in stacks, and long-term cardiometabolic outcomes

Kyowa is the maker of branded ingredients including Cognizin Citicoline, Pantesin Pantethine, Setria Glutathione, as well as Sustamine L-Alanyl-L-Glutamine

References Wu G, et al

Gut microbiota and brain alterations in a translational anorexia nervosa rat model

The effect of drinking water pH on the human gut microbiota and glucose regulation: results of a randomized controlled cross-over intervention